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사람들

Stem Cell and Regenerative
Biology Graduate Program

임성갑

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Prof Info.

임성갑Sung Gap Im

생명화학공학과

줄기세포 및 분화연구 조직공학 및 오가노이드

Lab Info.

기능성 박막 연구실(Functional Thin Films Lab, FTFL)은 새로운 고분자 증착 방법인 유도 화학 기상 증착법(initiated chemical vapor deposition, iCVD)을 활용하여 혁신적인 박막 소재와 구조를 개발하고 있습니다.
iCVD는 탁월한 조성 제어와 균일성을 갖춘 기능성 고분자 필름을 증착할 수 있는 공정입니다.
또한, iCVD 방법은 조직 배양 폴리스타이렌, 직물, 멤브레인과 같은 열 및 용매에 민감한 기판에 손상을 주지 않습니다.
이 용매가 없는 공정은 기판을 손상시키지 않으면서 생체 적합성 고분자 코팅을 제공합니다.
우리 연구실은 줄기세포 배양과 분화 및 조직 공학을 위한 기능성 고분자 코팅의 개발에 주력하고 있습니다.
Functional Thin Films Lab (FTFL) is developing innovative thin film materials and structures using a new polymer deposition method called initiated chemical vapor deposition (iCVD). iCVD is a process capable of depositing functional polymer films with exceptional compositional control and uniformity. Additionally, the iCVD method does not damage substrates sensitive to heat and solvents, such as tissue culture polystyrenes, fabrics, and membranes. This solvent-free process provides biocompatible polymer coatings without damaging the substrates. Our lab is focusing on developing functional polymer coatings for stem cell culture and differentiation as well as tissue engineering.

Profile.

  • 2020.1 – 현재 Professor, CBE, Korea Advanced Institute of Science and Technology, Daejeon, Korea
  • 2014.9 – 2020.2 Associate Professor, CBE, Korea Advanced Institute of Science and Technology, Daejeon, Korea
  • 2010.8 – 2014.8 Assistant Professor, CBE, Korea Advanced Institute of Science and Technology, Daejeon, Korea
  • 2017.7 – 2018.7 Visiting Professor, University of Illinois Urbana-Champaign, Champaign, IL, USA
  • 2010.1 – 2010.8 Postdoctoral Researcher in Dept. of Critical Care, Children’s Hospital Boston, Harvard Medical School, Boston, MA, USA
  • 2009.1 – 2009.12 Postdoctoral Research Associate in Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
  • 2002.10 – 2004.3 Researcher, LG Display, Anyang, Korea
  • 1999.1 – 2002.10 Research Engineer, LG Chemicals/Research Park, Daejeon, Korea

Education.

  • Ph.D. 2009 Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
  • M. S. 1999 Department of Chemical Engineering, Seoul National University, Seoul, Korea
  • B. S. 1997 Department of Chemical Engineering, Seoul National University, Seoul, Korea

Main Research areas.

  • In vitro polymer surface modification for enhanced cell performance
  • Development of an organoid culture platform excluding xenogeneic materials
  • Cell sheet engineering for stem cell therapeutic applications

Main Publications.

  • "Long-term Culture of Human Pluripotent Stem Cells in Xeno-Free Condition Using Functional Polymer Films ", Y. Cho, H. Lee, W. Jeong, K. Jung, S. Lee, S. Park, J. Yeun, O. Kwon, J. Son, T. Lee, M-Y Son, S. Im, Advanced Materials, 2024, 2403952.
  • "Hydrophobic surface induced pro-metastatic cancer cells for in vitro extravasation models", M. Lee, S. Kim, S. Lee, J. Son, J. Park, S. Park, T. Lee, S. Im, and J. S. Jeon, Bioactive Materials, 2024, 34, 401-413.
  • "N-Cadherin Adhesive Ligation Regulates Mechanosensitive Neural Stem Cell Lineage Commitment in 3D Matrices", J. Baek, S. Kumar, D. V. Schaffer, S. Im, Biomaterials Science, 2022, 10(23), 6768-6777
  • "Surface Hydrophobicity Modulates the Key Characteristics of Cancer Spheroids through the Interaction with the Adsorbed Proteins", M. Lee, Y. Kim, S. Yu, S. Lee, J. Son, T. Lee, Y. Cho, J. H. Shin, E. Lee, and S. Im, Advanced Functional Materials, 2021, 31(31), 2100775
  • "A Surface-Tailoring Method for Rapid Non-thermosensitive Cell Sheet Engineering via Functional Polymer Coatings", J. Baek, Y. Cho, H-J Park, G. Choi, J. Lee, M. Lee, S. Yu, S-W Cho, E. Lee, and S. Im, Advanced Materials, 2020, 32(16), 1907225