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Stem Cell and Regenerative
Biology Graduate Program
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Hanseul Yang양한슬
Department of Biological Sciences
Stem Cell and Differentiation Research Developmental and disease models
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The Laboratory of Stem Cell and Tissue Regeneration is interested in how stem cells in our body function in tissue homeostasis and regeneration.
Using skin and endometrium as model tissues, we investigate the mechanisms of adult stem cell activation and differentiation during tissue development and regeneration.
The aim is to identify novel target molecules for various diseases and to propose new therapeutic approaches.
Using skin and endometrium as model tissues, we investigate the mechanisms of adult stem cell activation and differentiation during tissue development and regeneration.
The aim is to identify novel target molecules for various diseases and to propose new therapeutic approaches.
- 2020.9 - Present Assistant Professor, Department of Biological Sciences, KAIST
- 2004.3 - 2008.2 B.S. Department of Biological Sciences, KAIST
- 2008.9 - 2010.2 M.S. Department of Biological Sciences, KAIST
- 2013.9 - 2018.6 Ph.D. Rockefeller University
- 2018.7 - 2020.8 Postdoc. Rockefeller University
- Adult stem cell biology
- Epigenetic regulation of stem cell
- Single cell analysis
- Yang H, Adam RC, Ge Y, Hua ZL, Fuchs E. Epithelial-mesenchymal micro-niches govern stem cell lineage choices. Cell 2017;169(3), 483-496
- Adam RC*, Yang H*, Ge Y, Lien WH, Wang P, Zhao Y, Polak L, Levorse J, Baksh SC, Zheng D, Fuchs E. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression. Cell Stem Cell, 2018;22(3), 398-413 (*Co-first authors)
- Adam RC*, Yang H*, Ge Y, Infarinato NR, Gur-Cohen S, Miao Y, Wang P, Zhao Y, Lu CP, Kim JE, Ko JY, Paik SS, Gronostajski RM, Kim J, Krueger JG, Zheng D, Fuchs E. NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices. Nature Cell Biology, 2020;22(6), 640-650. (*Co-first authors)
- Yang H*, Schramek D*, Adam RC, Keyes BE, Wang P, Zheng D, Fuchs E. ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas.eLIFE2015;4, e10870 (*Co-first authors)